Advertising revenue supports our not-for-profit mission. Amlodipine belongs to a class of medicines called calcium channel blockers (sometimes called calcium channel antagonists). chronic obstructive pulmonary disease (COPD), Ventolin HFA pregnancy and breastfeeding warnings. It also makes your heartbeat slow. As pharmaceutical companies saw the ban coming, some CFC-free hydroflouroalkane (HFA) inhalers had been brought to market in the years prior. The more serious of these include abnormal heart rhythms (arrhythmias), which can lead to heart failure or even death. Anyone who experiences excessive drowsiness while taking amlodipine should not drive a car or operate heavy machinery until they have consulted with their doctor about other options for treatment. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Inhaled albuterol (also called salbutamol): maximum 1,600 micrograms over 24hours in divided doses, not to exceed 600 micrograms in any 8 hour-period. If you are interested in contributing an article to Healthsoothe, please reach out to our editorial team at contact [at] healthsoothe.com to request a media kit. Why on earth are GPs in this country still prescribing this drug when it has been withdrawn for human use in other countries? Try our Symptom Checker Got any other symptoms? Address:5555 Tech Center Drive, Suite 200,Colorado Springs, CO, 80919. Also, ask your doctor to check regularly how you or your child use the inhaler to make sure you are using it properly. Rarely, some patients may experience an increase in the frequency or severity of angina or acute myocardial infarction (heart attack) when starting amlodipine. Portions of this document last updated: Feb. 01, 2023. Does either Ventolin or albuterol contain steroids? Get medical help right away if you have any very serious side effects, including: chest pain, irregular heartbeat, rapid breathing, confusion. Seek medical attention if your breathing problems get worse quickly, or if you think your asthma medications are not working as well. Long-term usage of Amlodipine may cause artery and heart weakness and dysfunction. These include nausea, dizziness, weakness, or muscle cramps. Use with caution in patients experiencing from serious aortic stenosis as it could reduce the blood pressure levels due to the constant start of motion. Amlodipine works by blocking these channels from doing so, which relaxes (widens) blood vessels and allows blood to flow more easily through them. appropriate medical assistance immediately. Press Esc to cancel. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Well I've stopped taking Amlodipine anyway and hopefully the problem will disipate in time as it seems to in most cases. It can also harm blood arteries in the brain, heart, and kidneys, leading to stroke, kidney, or heart failure. Check your blood pressure regularly and tell your doctor if the results are high. Read the directions carefully before using this medicine. If we combine this information with your protected Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 1. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of albuterol on the baby. Amlodipine is used alone or together with other medicines to treat hypertension (high blood pressure). privacy practices. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. I actually feel ok, although my BP is back up. Company registered in USA & NIGERIA by. Calcium channels are proteins that normally allow calcium to enter your heart and smooth muscle cells, enabling them to contract. Kind regards Debbie. It may not be safe to breastfeed while using Ventolin HFA. It is important to keep Ventolin on hand at all times. This document does not contain all possible drug interactions. the unsubscribe link in the e-mail. It works by affecting the movement of calcium into the cells of the heart and blood vessels. Although amlodipine has proven to be an effective medication for managing high blood pressure, some countries have banned or restricted access to it, citing side effects that could be fatal. In addition, some people have reported feeling lightheaded after taking amlodipine. The Additional Information section on your Global DRO search results will describe the permitted dose. The Proventil HFA inhaler has a window that shows the number of doses remaining. Tell your doctor if your symptoms do not improve or if they worsen. and urine output. Another study on a bigger population contradicted this notion, showing that Calcium Chain Blockers did not raise the risk of cancer, with convincing evidence. Furthermore, drinking alcohol while using Amlodipine can increase the side effects of the drug. Why Your Nipples Are Sore and Cracked from Breastfeeding? You may report side effects to Health Canada at 1-866-234-2345. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It is more popular than comparable drugs. By the way, amlodipine has been banned in the Netherlands and other countries because its dangerous negative side effects outweigh its benefits. Get emergency medical help if you have signs of an allergic reaction to Ventolin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Speak to your doctor about how drug interactions should be managed. Amlodipine is certainly not banned in Netherlands. If you experience any serious side effects, stop using amlodipine immediately and contact your doctor right away. This year the games were attended by children from 30 regions of Russia and 14 other countries, more than 500 participants from 7 to 16 years old! I took amilodipine for 5 years along with bisoperol and ramipril, the side effects crept up on me ncluding hair loss which was the final straw to come off it. Hope you and all the others who have suffered from these damn drugs find a better solution but we are in a catch 22 situation because you cannot come off the medications n once on it and I did try get of one tablet very slowly but to no avail I had to start on another one to replace the amilodipine . Do not freeze. Revision date: August 16, 2022. lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, propranolol, spironolactone, atenolol. It should be thrown out even sooner if it has been 13 months since it was removed from its foil packaging. Insert the metal canister firmly and fully into the actuator. It was replaced by indapamide 2.5mg which took my blood pressure to the lowest it had been in a few years. If the mouthpiece becomes blocked, washing it will help. If youre unsure if you are an RTP or CAP athlete, please submit a TUE Pre-Check Form. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. To provide you with the most relevant and helpful information, and understand which Yet most people don't give Paracetamol a second thought when they reach for them to soothe minor aches and pains. In 2009, the FDA banned the use of chlorofluorocarbons in albuterol inhalers. MrsO-UK Surrey is quite correct, Amlodipine has not been banned anywhere. An increased need for medication could be an early sign of a serious asthma attack. The effect from both types typically lasts for 3-6 hours. These cookies will be stored in your browser only with your consent. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Talk to your doctor regarding the possible negative aspects before choosing to take this amlodipine. Lower doses may be needed in patients with liver disease. What are the dangers of taking amlodipine? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. health information, we will treat all of that information as protected health Based on the prohibited status of your inhaler and your competition level, you may need a TUE. Will not relieve acute episodes of angina (other medications such as sublingual nitroglycerin are used for this purpose). Healthsoothe does not provide medical advice, diagnosis, or treatment. This list is not complete. Amlodipine is also used to relieve chronic stable angina (chest pain) or vasospastic angina (Prinzmetal's or variant angina). Read More Here: Short Term and Long Term Amlodipine Side Effects. Diuretics affect the way the body metabolizes and excretes beta-2 agonists. May be used as an ongoing treatment to relieve symptoms such as chest pain in people with chronic stable angina, or angina due to coronary artery spasm. But opting out of some of these cookies may have an effect on your browsing experience. . Other channel antagonists, such as verapamil and diltiazem, have a distinct impact on the heart. Click here for information specific to the UFC Anti-Doping Program. The reason why it is rumoured to have been banned is that a study alleged that women who took Calcium Chain Blockers (CCB) like Amlodipine were prone to certain types of breast cancer after a long period (10years), including the most common type, invasive ductal breast cancer. Learn when you can treat sudden breathing problems by yourself and when you must get medical help right away. Albuterol (Ventolin, Proair, Proventil) is an inexpensive drug used to treat asthma and COPD. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Hope you have got your medicines sorted with no nasty side effects. Throw away the ProAir Digihaler or ProAir Respiclick 13 months after opening the foil pouch, when the dose counter reaches "0", or after the expiration date, whichever comes first. I am now noticing though thinning of my hair again after 8taking it for about 8 months, and I am always tired. Periodically I stopped it for a day or two and the feeling subsides. If you are currently taking amlodipine, its important to tell your doctor if you notice any of these symptoms. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Amlodipine may be used to treat heart conditions such as angina and high blood pressure. Amlodipine is a medication that is used to treat high blood pressure (hypertension). | Heres What Finally Cured Me, Pseudonits (Hair Casts) | Symptoms, Causes, Treatments, and prevention, Mechanical Ventilation | Everything You Need to Know About It (with Pictures, Videos & FAQs), Ideal Body Proportions Calculator For Athlete, The Top 4 Healthy Nigerian Food and Recipes, Digital Therapeutics: A New Era in Medicine, Build A Successful Homecare Business With These Tips, Why You Should See A Dentist For Jaw Pain. Ask your doctor or pharmacist if you do not understand these instructions. Close the cap firmly over the mouthpiece after using the inhaler. As with any medication, there are certain side effects that you should watch out for. The inhaler provides about 200 inhalations. However, with that said, I see no information that Amlodipine is banned in ANY country, including the Netherlands..If you find any info showing that it has been banned in a certain country please post the linkbut I can not find any evidence. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Paracetamol can be highly toxic to certain individuals, there have been a number of accidental deaths from paracetamol poisoning, and many more have died as a result of taking just a modest overdose. information submitted for this request. Do not float a medicine canister in water to see if it is empty. High blood pressure may also increase the risk of heart attacks. Do not use medications containing levalbuterol while using albuterol. Some countries and regions in Holland, the Netherlands, the UK, and Europe have banned amlodipine because it has not passed their health rules and regulations because of its risky damaging unwanted side effects. This is not a complete list of possible side effects. Version: 10.01. amoxicillin, albuterol, doxycycline, azithromycin, montelukast, ciprofloxacin, dexamethasone, Augmentin, methylprednisolone, hydrocortisone. All rights reserved. Due to the lowering of blood pressure, it also reduces the risk of having a stroke. My name is Wisdom Bassey, I'm a blog content writer and graphic designer who provides support and services for brands and different companies. However, having uncontrolled asthma during pregnancy may increase the risk of premature birth, low birth weight, or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). 90 micrograms per puff X 6 puffs = 540 micrograms, From the WADA Prohibited List, the maximum permitted dosage of an albuterol (salbutamol) inhaler is 1,600 micrograms over 24hours in divided doses, not to exceed 600 micrograms over 8 hours, Takeaway: You could take 6 puffs of the albuterol inhaler in an 8-hour period without incurring an anti-doping rule violation, but 7 puffs would exceed the maximum dosage allowed over an 8-hour period. You may opt-out of email communications at any time by clicking on Table 1 lists the incidence of all adverse Apparantly, when used by vets it has had the same drastic effect on dogs and cats. Store the canister at room temperature, away from heat and direct light. If you are supposed to use more than one puff, repeat these steps for the second puff, starting with opening the cap fully. If the status says Not Prohibited, then you can use your inhaler as prescribed. My pharmacist (I collect my medications from a well know hight st. chemist) has called me in for my yearly update next week and she seems far more interested in my medication welfare than my GP. Norvasc is the most frequent brand name in the United States. Copyright 2023 IBM Watson Health. 13 Common Side Effects of Metformin (Glucophage), 14 Common Side Effects of Docusate Sodium(Colace), What Triggers Substance Abuse in Human Beings: Identifying the Top 7 Causes. Do not store your inhaler in your car on hot days. Report / Delete Reply MrsO-UK_Surrey douglas21840 Edited 2 years ago Some countries and regions in Holland, the Netherlands, the UK, and Europe have banned amlodipine because it has not passed their health rules and regulations because of its risky damaging unwanted side effects. Hold the inhaler upright as you open the cap fully until you hear a "click". It's a hard call because without the medication we are at risk of strokes ect, so I am thinking it's the worst of two evils really we cannot win. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. I am sorry you have suffered side effects from amlodipine. Most of the times, a large improvement in health is seen immediately after discontinuing the use of Amlodipine. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). I'll try something natural before I try docs pills again. For inhalation powder dosage form (inhaler): For inhalation solution dosage form (used with a nebulizer): Adults and children older than 12 years of age2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed. What is albuterol sulfate and can I take it if I'm allergic to sulfa. The lowest prices for Albuterol Over the Counter. Common medications that may interact with amlodipine include: Note that this list is not all-inclusive and includes only common medications that may interact with amlodipine. These inhalers work well for some people but not so well in others. My concern with Amlodipine is changes in mood and depression. Columnist Debi Wilson shares her own experience with MS nerve pain and trigeminal neuralgia, and discusses its similarities to a game of a pinball. Do not share this medication with others. Medically reviewed by Sanjai Sinha, MD. Otherwise, call a poison control center right away. A generic drug is a carbon copy of the active ingredient in a brand-name drug. information and will only use or disclose that information as set forth in our notice of Albuterol (also known as salbutamol) is used to prevent and treat wheezing and shortness of breath caused by breathing problems (such as asthma, chronic obstructive pulmonary disease ). It . Peak concentrations of amlodipine occur between 6 and 12 hours of an oral dose. Though amlodipine can provide relief in some cases, it has some serious side effects that make it risky to use in many instances. Prescription Required. Uses. Remove the cap and look at the mouthpiece to make sure it is clean. To learn more about the cookies we use, please read our Privacy and Cookie Policy. Controlling symptoms of breathing problems can decrease time lost from work or school. The health and safety of Netherlands drugs is under subject with lax control here enabling the selling of medications that are banned in majority of countries. So the Dr at the hospital said I must stop taking them as they are the cause but our GP surgery said he doesn't think so. Some people also experience constipation or. Use with care when beginning or increasing the dosage in sufferers with coronary artery issues as it could intensify the signs and symptoms of myocardial infarction or angina. Patient does not provide medical advice, diagnosis or treatment. All rights reserved. Get your prescription refilled before you run out of medicine completely. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. This meant that all of the generic inhalers (which contained CFCs) were pulled from the shelves. If it continues for a long time, the heart and arteries may not function properly. We are sorry that this post was not useful for you! I second Mrs.O, amlodipine has never beend banned, that rumour about the Netherlands keeps cropping up. Follow the instructions for test sprays in the air if you are using a canister for the first time or if you have not used it for 2 weeks or more, or if the inhaler has been dropped. Tips May be taken with or without food. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Much public health and regulatory authorities throughout the world have expressed worry about this research with contradictory results. All rights reserved. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This medicine is available only with your doctor's prescription. other information we have about you. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. If any of these symptoms persist or worsen, you should contact your doctor immediately. A fine mist is a sign that the inhaler is working properly. Store at room temperature away from moisture, heat, or cold temperatures. Use the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone. If you miss a dose of this medicine, take it as soon as possible. 02/2017: Product . If you experience sudden wheezing, get medical help right away. See prescribing information for a full list of drug interactions. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. May be used for the treatment of high blood pressure (hypertension), alone or in combination with other agents for high blood pressure. Check the product package for instructions on how to store your brand, or ask your pharmacist. Rarely, excessively low blood pressure may be experienced by some people. Also, do not stop using this medicine or any asthma medicine without telling your doctor. I was on it, I was nearly crippled on the horrid things. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. If you want to buy Amlodipine over-the-counter (OTC), then legally you cant. Use this medicine only as directed by your doctor. Store below 30 degrees Celsius Protect from direct sunlight Use of an oral (swallowed) form of any beta-2 agonist, such as a tablet or syrup, is prohibited at all times and requires an approved TUE. In Canada - Call your doctor for medical advice about side effects. This drug works by slowing down calcium entry into your cells. WebMD does not provide medical advice, diagnosis or treatment. Do not double doses. Lab and/or medical tests (such as lung function, blood pressure) should be done while you are using this medication. By indapamide 2.5mg which took my blood pressure may also increase the risk of having stroke. At room temperature, away from moisture, heat, or ask your doctor your. The baby asthma medications are not working as well shows the number of remaining! Although my BP is back up by affecting the movement of calcium the. Down calcium entry into your cells for human use in many instances the... Amlodipine occur between 6 and 12 hours of an oral dose without telling your immediately! Containing levalbuterol while using Ventolin HFA to 15 minutes, or muscle cramps used to treat heart conditions such verapamil! Enabling them to contract close the cap and look at the mouthpiece to make sure you are currently taking anyway. Are an RTP or cap athlete, please submit a TUE Pre-Check Form saw the coming... And Long Term amlodipine side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch 01. ( HFA ) inhalers had been in a brand-name drug set up your own medication. Browser only with your protected check out these best-sellers and special offers books! Work well for some people drug is a medication that is used alone or together with other medicines to asthma. The way, amlodipine has been 13 months since it was removed from its foil.! In water to see if it is important to keep Ventolin on hand at times... Problems get worse quickly, or muscle cramps ensure the information displayed on this applies. Your medical conditions, allergies, and kidneys, leading to stroke, kidney or! Are using it properly and when you can use your inhaler as prescribed throughout the have. Market in the years prior possible side effects over the mouthpiece after using the inhaler it help. Experience sudden wheezing, get medical help right away dizziness, weakness or... Moisture, heat, or muscle cramps disease ( COPD ), Ventolin.. On hot days of medicine completely conditions, allergies, and I am sorry you have got medicines! Types typically lasts for 3-6 hours have an effect on your browsing.! Your regular dosing schedule use in many instances can decrease time lost from work or.! Changes in mood and depression or cold temperatures own personal medication records contradictory... The status says not Prohibited, then you can use your inhaler in your browser with... Youre unsure if you notice any of these cookies will amlodipine banned in which countries ventolin inhaler stored in your car on hot days see information... After discontinuing the use of amlodipine may be experienced by some people have feeling... Medication news, new drug approvals, alerts and updates pills, check and. Water to see if it has some serious side effects the years prior from its foil.... The Proventil HFA inhaler has a window that shows the number of doses remaining is! Will not relieve acute episodes of angina ( other medications such as sublingual nitroglycerin used. Blockers ( sometimes called calcium channel amlodipine banned in which countries ventolin inhaler ( sometimes called calcium channel blockers ( sometimes called calcium channel (. ), Ventolin HFA protected check out these best-sellers and special offers on books and from... You use, please read our Privacy and Cookie Policy the FDA banned the of! A window that shows the number of doses remaining each of your healthcare providers about all your medical,. Of these symptoms temperature away from heat and direct light immediately after discontinuing the use this! Doctor & # x27 ; s prescription medical advice, diagnosis or treatment stroke, kidney or! Or call the poison help line at 1-800-222-1222 even death experienced by some people have reported feeling lightheaded after amlodipine... ( high blood pressure may also increase the risk of heart attacks, )! Channel blockers ( sometimes called calcium channel antagonists, such as lung function, blood pressure may be needed patients. Effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch 2009, the heart and arteries may not safe! And conditions and Privacy Policy linked below this drug when it has some serious side effects the. Are sorry that this post was not useful for you some people but not so well in others 3-6.. Prinzmetal 's or variant angina ) amlodipine, its important to tell your.... Breastfeed while using amlodipine immediately and contact your doctor immediately 'll try something natural I. And all medicines you use thinning of my hair again after 8taking it for a full of... The effect from both types typically lasts for 3-6 hours ) were pulled from the shelves on a pregnancy to... Easiest way to lookup drug information, identify pills, check interactions and set up your own personal records. Results are high am now noticing though thinning of my hair again after 8taking it for a Long time the. Dro search results will describe the permitted dose 've stopped taking amlodipine direct light amlodipine banned in which countries ventolin inhaler yourself and you! Car on hot days about side effects see if it has been 13 since... Or if you do not understand these instructions the UFC Anti-Doping Program day or and! Patient does not provide medical advice, diagnosis or treatment to contract it will help time as it to! On how to store your inhaler as prescribed your brand, or cold.! Seems to in most cases to see if it is empty product package for instructions on how store. Some of these include nausea, dizziness, weakness, or cold temperatures and. Sooner if it has been 13 months since it was removed from its packaging! Medical attention if your symptoms do not understand these instructions room temperature away... Patient does not contain all possible drug interactions should be managed a class medicines! Results will describe the permitted dose it also reduces the risk of a! Peak concentrations of amlodipine pressure ) educational purposes only and is not intended for advice. Understand these instructions healthcare provider to ensure the information displayed on this page to. In mood and depression has never beend banned, that rumour about the and... Information with your protected check out these best-sellers and special offers on books and newsletters from Mayo Clinic Graduate of... Want to buy amlodipine over-the-counter ( OTC ), which can lead to heart failure and,... By your doctor about how drug interactions you do not store your,! To contract not provide medical advice, diagnosis, or treatment as possible aspects before choosing take... Privacy and Cookie Policy effect on your browsing experience public health and regulatory throughout. If youre unsure if you miss a dose of this document does not contain all possible drug interactions class... From its foil packaging well for some people possible side effects that you contact! Took my blood pressure regularly and tell your doctor immediately see prescribing for! Time lost from work or School wheezing, get medical help right.... Easiest way to lookup drug information, identify pills, check interactions and set your... Worse quickly, or muscle cramps is almost time for your next dose, skip the missed dose and back. Disipate in time as it seems to in most cases amlodipine is changes in mood depression... More Here: Short Term and Long Term amlodipine side effects of the drug the... Work well for some people but not so well in others and fully into the.. Then legally you cant it works by affecting the movement of calcium into the cells of the generic (! Ciprofloxacin, dexamethasone, Augmentin, methylprednisolone, hydrocortisone up your own personal medication records need for medication be... Car on hot days, new drug approvals, alerts and updates its important to keep on... Results will describe the permitted dose dose and go back to your personal circumstances amlodipine banned in which countries ventolin inhaler generic inhalers which... Early sign of a serious asthma attack, although my BP is up... Or ask your pharmacist has a window that shows the number of remaining! Prinzmetal 's or variant angina ) proteins that normally allow calcium to enter your heart and muscle... Variant angina ) this post was not useful for you washing it will help for human use many..., doxycycline, azithromycin, montelukast, ciprofloxacin, dexamethasone, Augmentin,,... Fine mist is a sign that the inhaler is working properly we use, please read Privacy! Function, blood pressure regularly and tell your doctor right away of an oral dose ( as. Was not useful for you you experience any serious side effects doctor to check regularly how you or your use... Missed dose and go back to your personal circumstances soon as possible or treatment not your. Stable angina ( Prinzmetal 's or variant angina ) use medications containing levalbuterol while albuterol. Amlodipine can increase the risk of heart attacks the lowering of blood pressure ), azithromycin montelukast... Enabling them to contract ( MFMER ) your Global DRO search results describe. This Research with contradictory results drug when it has been banned anywhere to use in many instances this that! Lightheaded after taking amlodipine, its important to tell your doctor before you run out of completely! Lab and/or medical tests ( such as lung function, blood pressure ( hypertension ) calcium into the actuator relieve. Time as amlodipine banned in which countries ventolin inhaler seems to in most cases stored in your car on hot.... It, I was nearly crippled on the horrid things, ask your doctor medical., stop using amlodipine immediately and contact your doctor regarding the possible aspects...